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The microneedling creates micro-channels that deliver copper peptides directly to the dermal papilla the exact target cells identified in Pyo et al.'s 2007 work

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We must first understand that in obesity and other chronic metabolic conditions like type II diabetes mellitus, the expression of NNMT is elevated

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In lab and clinical research, its been observed to activate fibroblasts (the cells that produce collagen), increase glycosaminoglycan synthesis (which helps skin retain water), modulate matrix metalloproteinases (MMPs, the enzymes that break down old tissue), and act as a copper cofactor in antioxidant pathways